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Icariin Treatment Protects Against Gentamicin-Induced Ototoxicity via Activation of the AMPK-SIRT3 Pathway

Ototoxicity is a serious health problem that greatly affects millions of people worldwide. This condition is caused by the entry of aminoglycosides into auditory hair cells, subsequently inducing reactive oxygen species (ROS) production and accumulation. Several strategies have been adopted to overc...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Hu, Yue, Ma, Xiulan
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930742/
https://ncbi.nlm.nih.gov/pubmed/33679402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.620741
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