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Icariin Treatment Protects Against Gentamicin-Induced Ototoxicity via Activation of the AMPK-SIRT3 Pathway

Ototoxicity is a serious health problem that greatly affects millions of people worldwide. This condition is caused by the entry of aminoglycosides into auditory hair cells, subsequently inducing reactive oxygen species (ROS) production and accumulation. Several strategies have been adopted to overc...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Hu, Yue, Ma, Xiulan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930742/
https://ncbi.nlm.nih.gov/pubmed/33679402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.620741
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