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Recent Advances in Silent Gene Cluster Activation in Streptomyces

Natural products (NPs) are critical sources of drug molecules for decades. About two-thirds of natural antibiotics are produced by Streptomyces. Streptomyces have a large number of secondary metabolite biosynthetic gene clusters (SM-BGCs) that may encode NPs. However, most of these BGCs are silent u...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Liu, Zhenyu, Zhao, Yatong, Huang, Chaoqun, Luo, Yunzi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930741/
https://ncbi.nlm.nih.gov/pubmed/33681170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2021.632230
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