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LRG1 promotes epithelial-mesenchymal transition of retinal pigment epithelium cells by activating NOX4

AIM: To investigate the effect of leucine-rich-alpha-2-glycoprotein 1 (LRG1) on epithelial-mesenchymal transition (EMT) in retinal pigment epithelium (RPE) cells, and to explore the role of NADPH oxidase 4 (NOX4). METHODS: RPE cells (ARPE-19 cell line) were treated with transforming growth factor-β1...

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Detalhes bibliográficos
Publicado no:Int J Ophthalmol
Main Authors: Zhou, Li, Shi, De-Peng, Chu, Wen-Juan, Yang, Ling-Ling, Xu, Hai-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: International Journal of Ophthalmology Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930530/
https://ncbi.nlm.nih.gov/pubmed/33747808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18240/ijo.2021.03.03
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