In Vivo Priming of Peritoneal Tumor-Reactive Lymphocytes With a Potent Oncolytic Virus for Adoptive Cell Therapy

Adoptive cell therapy (ACT) using autologous tumor infiltrating lymphocytes (TIL) achieves durable clinical benefit for patients from whom these cells can be derived in advanced metastatic melanoma but is limited in most solid tumors as a result of immune escape and exclusion. A tumor microenvironme...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Giehl, Esther, Kosaka, Hiromichi, Liu, Zuqiang, Feist, Mathilde, Kammula, Udai S., Lotze, Michael T., Ma, Congrong, Guo, Zong Sheng, Bartlett, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930493/
https://ncbi.nlm.nih.gov/pubmed/33679747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.610042
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