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Acquired MET D1228N Mutations Mediate Crizotinib Resistance in Lung Adenocarcinoma with ROS1 Fusion: A Case Report

Patients with non‐small cell lung cancer (NSCLC) containing ROS1 fusions can have a marked response to the ROS1‐targeted tyrosine kinase inhibitors (TKIs), such as crizotinib. Common resistance mechanisms of ROS1‐fusion targeted therapy are acquired mutations in ROS1. Along with the use of next‐gene...

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Bibliografske podrobnosti
izdano v:Oncologist
Main Authors: Wang, Yu, Chen, Zheng, Han, Xiao, Li, Jiamei, Guo, Honglin, Shi, Junping
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Inc. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930416/
https://ncbi.nlm.nih.gov/pubmed/33000474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/onco.13545
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