MET Genomic Alterations in Head and Neck Squamous Cell Carcinoma (HNSCC): Rapid Response to Crizotinib in a Patient with HNSCC with a Novel MET R1004G Mutation

Identification of effective targeted therapies for recurrent/metastatic head and neck squamous cell carcinoma (HNSCC) remains an unmet medical need. A patient with platinum‐refractory recurrent oral cavity HNSCC underwent comprehensive genomic profiling (CGP) that identified an activating MET mutati...

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Dades bibliogràfiques
Publicat a:Oncologist
Autors principals: Chu, Lisa Pei, Franck, Debra, Parachoniak, Christine A., Gregg, Jeffrey P., Moore, Michael G., Farwell, D. Gregory, Rao, Shyam, Heilmann, Andreas M., Erlich, Rachel L., Ross, Jeffrey S., Miller, Vincent A., Ali, Siraj, Riess, Jonathan W.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Inc. 2019
Matèries:
Precision Medicine Clinic: Molecular Tumor Board
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795166/
https://ncbi.nlm.nih.gov/pubmed/31391294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2019-0230
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