MET Genomic Alterations in Head and Neck Squamous Cell Carcinoma (HNSCC): Rapid Response to Crizotinib in a Patient with HNSCC with a Novel MET R1004G Mutation

Identification of effective targeted therapies for recurrent/metastatic head and neck squamous cell carcinoma (HNSCC) remains an unmet medical need. A patient with platinum‐refractory recurrent oral cavity HNSCC underwent comprehensive genomic profiling (CGP) that identified an activating MET mutati...

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Bibliografski detalji
Izdano u:Oncologist
Glavni autori: Chu, Lisa Pei, Franck, Debra, Parachoniak, Christine A., Gregg, Jeffrey P., Moore, Michael G., Farwell, D. Gregory, Rao, Shyam, Heilmann, Andreas M., Erlich, Rachel L., Ross, Jeffrey S., Miller, Vincent A., Ali, Siraj, Riess, Jonathan W.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Inc. 2019
Teme:
Precision Medicine Clinic: Molecular Tumor Board
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795166/
https://ncbi.nlm.nih.gov/pubmed/31391294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2019-0230
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