JQ1 as a BRD4 Inhibitor Blocks Inflammatory Pyroptosis-Related Acute Colon Injury Induced by LPS

Endotoxemia is a severe inflammation response induced by infection especially bacterial endotoxin translocation, which severely increases mortality in combination with acute colon injury. Bromodomain-containing protein 4 (BRD4) is an important Bromo and Extra-Terminal (BET) protein to participate in...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Chen, Ling, Zhong, Xiaolin, Cao, Wenyu, Mao, Mingli, Li, Wei, Yang, Hui, Li, Menglin, Shi, Mengmeng, Zhang, Yuan, Deng, Yincheng, Zu, Xuyu, Liu, Jianghua
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930386/
https://ncbi.nlm.nih.gov/pubmed/33679744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.609319
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