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Beneficial effects of elafibranor on NASH in E3L.CETP mice and differences between mice and men

Non-alcoholic steatohepatitis (NASH) is the most rapidly growing liver disease that is nevertheless without approved pharmacological treatment. Despite great effort in developing novel NASH therapeutics, many have failed in clinical trials. This has raised questions on the adequacy of preclinical mo...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: van den Hoek, Anita M., Verschuren, Lars, Caspers, Martien P. M., Worms, Nicole, Menke, Aswin L., Princen, Hans M. G.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930243/
https://ncbi.nlm.nih.gov/pubmed/33658534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83974-8
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