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Quantitative intravital imaging in zebrafish reveals in vivo dynamics of physiological-stress-induced mitophagy

Mitophagy, the selective recycling of mitochondria through autophagy, is a crucial metabolic process induced by cellular stress, and defects are linked to aging, sarcopenia and neurodegenerative diseases. To therapeutically target mitophagy, the fundamental in vivo dynamics and molecular mechanisms...

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Détails bibliographiques
Publié dans:J Cell Sci
Auteurs principaux: Wrighton, Paul J., Shwartz, Arkadi, Heo, Jin-Mi, Quenzer, Eleanor D., LaBella, Kyle A., Harper, J. Wade, Goessling, Wolfram
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7929928/
https://ncbi.nlm.nih.gov/pubmed/33536245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.256255
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