The Activin/Follistatin-axis is severely deregulated in COVID-19 and independently associated with in-hospital mortality

BACKGROUND: Activins are members of the TGFβ-superfamily implicated in the pathogenesis of several immuno-inflammatory disorders. Based on our previous studies demonstrating that over-expression of Activin-A in murine lung causes pathology sharing key features of COVID-19, we hypothesized that Activ...

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Publicado no:J Infect Dis
Main Authors: Synolaki, Evgenia, Papadopoulos, Vasileios, Divolis, Georgios, Tsahouridou, Olga, Gavriilidis, Efstratios, Loli, Georgia, Gavriil, Ariana, Tsigalou, Christina, Tziolos, Nikolaos R, Sertaridou, Eleni, Kalra, Bhanu, Kumar, Ajay, Rafailidis, Petros, Pasternack, Arja, Boumpas, Dimitrios T, Germanidis, Georgios, Ritvos, Olli, Metallidis, Simeon, Skendros, Panagiotis, Sideras, Paschalis
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
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Major Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7928794/
https://ncbi.nlm.nih.gov/pubmed/33625513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiab108
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