DEAD-box RNA helicase Dbp4/DDX10 is an enhancer of α-synuclein toxicity and oligomerization

Parkinson’s disease is a neurodegenerative disorder associated with misfolding and aggregation of α-synuclein as a hallmark protein. Two yeast strain collections comprising conditional alleles of essential genes were screened for the ability of each allele to reduce or improve yeast growth upon α-sy...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Genet
Prif Awduron: Popova, Blagovesta, Wang, Dan, Pätz, Christina, Akkermann, Dagmar, Lázaro, Diana F., Galka, Dajana, Kolog Gulko, Miriam, Bohnsack, Markus T., Möbius, Wiebke, Bohnsack, Katherine E., Outeiro, Tiago F., Braus, Gerhard H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2021
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7928443/
https://ncbi.nlm.nih.gov/pubmed/33657088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009407
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