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Diastereo- and Enantioselective CuH-Catalyzed Hydroamination of Strained Trisubstituted Alkenes

Amine-substituted cyclobutanes and cyclopropanes are important substructures in biologically active compounds. Moreover, many of the cycloalkane units bear multiple substituents and stereocenters. Therefore, synthetic methods that produce polysubstituted aminocyclobutanes and aminocyclopropanes in a...

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Bibliographic Details
Published in:ACS Catal
Main Authors: Feng, Sheng, Hao, Hua, Liu, Peng, Buchwald, Stephen L.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7928433/
https://ncbi.nlm.nih.gov/pubmed/33664986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.9b04871
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