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Identification of Tumor Mutation Burden and Immune Infiltrates in Hepatocellular Carcinoma Based on Multi-Omics Analysis

We aimed to explore the tumor mutational burden (TMB) and immune infiltration in HCC and investigate new biomarkers for immunotherapy. Transcriptome and gene mutation data were downloaded from the GDC portal, including 374 HCC samples and 50 matched normal samples. Furthermore, we divided the sample...

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Vydáno v:Front Mol Biosci
Hlavní autoři: Yin, Lu, Zhou, Liuzhi, Xu, Rujun
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7928364/
https://ncbi.nlm.nih.gov/pubmed/33681288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.599142
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