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Identification of Tumor Mutation Burden and Immune Infiltrates in Hepatocellular Carcinoma Based on Multi-Omics Analysis

We aimed to explore the tumor mutational burden (TMB) and immune infiltration in HCC and investigate new biomarkers for immunotherapy. Transcriptome and gene mutation data were downloaded from the GDC portal, including 374 HCC samples and 50 matched normal samples. Furthermore, we divided the sample...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Yin, Lu, Zhou, Liuzhi, Xu, Rujun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7928364/
https://ncbi.nlm.nih.gov/pubmed/33681288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.599142
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