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Tau Deletion Prevents Cognitive Impairment and Mitochondrial Dysfunction Age Associated by a Mechanism Dependent on Cyclophilin-D

Aging is an irreversible process and the primary risk factor for the development of neurodegenerative diseases, such as Alzheimer’s disease (AD). Mitochondrial impairment is a process that generates oxidative damage and ATP deficit; both factors are important in the memory decline showed during norm...

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Bibliografski detalji
Izdano u:Front Neurosci
Glavni autori: Jara, Claudia, Cerpa, Waldo, Tapia-Rojas, Cheril, Quintanilla, Rodrigo A.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7928299/
https://ncbi.nlm.nih.gov/pubmed/33679286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.586710
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