Cistromic Reprogramming of the Diurnal Glucocorticoid Hormone Response by High-Fat Diet

The glucocorticoid receptor (GR) is a potent metabolic regulator and a major drug target. While GR is known to play integral roles in circadian biology, its rhythmic genomic actions have never been characterized. Here we mapped GR’s chromatin occupancy in mouse livers throughout the day and night cy...

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Publié dans:Mol Cell
Auteurs principaux: Quagliarini, Fabiana, Mir, Ashfaq Ali, Balazs, Kinga, Wierer, Michael, Dyar, Kenneth Allen, Jouffe, Celine, Makris, Konstantinos, Hawe, Johann, Heinig, Matthias, Filipp, Fabian Volker, Barish, Grant Daniel, Uhlenhaut, Nina Henriette
Format: Artigo
Langue:Inglês
Publié: 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7928064/
https://ncbi.nlm.nih.gov/pubmed/31706703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.10.007
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