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Inhibition of nucleophosmin 1 suppresses colorectal cancer tumor growth of patient -derived xenografts via activation of p53 and inhibition of AKT

The nucleophosmin 1 (NPM1) protein is frequently overexpressed in various cancers compared to normal tissues and represents a potential biomarker for maliganancy. However, its role in colorectal cancer (CRC) is still not fully understood. In this report, we show that NPM1 levels in CRC correlate wit...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cancer Biol Ther
Asıl Yazarlar: Yu, Angel C.Y., Chern, Yi-Jye, Zhang, Peter, Pasiliao, Clarissa C., Rahman, Mahbuba, Chang, George, Ren, Jianhua, Tai, Isabella T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7928027/
https://ncbi.nlm.nih.gov/pubmed/33446037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2020.1839278
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