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Effect of a Neuropilin-1-Derived Virus Receptor Trap on Enterovirus A71 Infection In Vitro

We discovered that neuropilin 1 (NRP1) is a new receptor candidate to mediate enterovirus A71 (EVA71) into cells. In the engineered form as a decoy receptor, NRP1 was able to recognize and neutralize EVA71 but not enterovirus D68 or coxsackievirus B3 (CVB3). NRP1 recognizes EVA71 through a novel dom...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Wang, Hsiang-Ching, Huang, Peng-Nien, Hung, Hui-Chen, Tseng, Sung-Nien, Chang, Chia-Chia, Tsai, Ya-Ru, Wang, Yun-Ming, Shih, Shin-Ru, Hsu, John Tsu-An
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927848/
https://ncbi.nlm.nih.gov/pubmed/33139286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00695-20
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