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Surface‐bound matrix metalloproteinase‐8 on macrophages: Contributions to macrophage pericellular proteolysis and migration through tissue barriers

OBJECTIVE: MMP‐8 binds to surface‐bound tissue inhibitor of metalloproteinase‐1 (TIMP‐1) on PMNs to promote pericellular proteolysis during the development of inflammatory diseases associated with tissue destruction. Little is known about the biology of MMP‐8 in macrophages. We tested the hypotheses...

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Bibliografiske detaljer
Udgivet i:Physiol Rep
Main Authors: Wang, Xiaoyun, Zhang, Duo, Fucci, Quynh‐Anh, Dollery, Clare M., Owen, Caroline A.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927794/
https://ncbi.nlm.nih.gov/pubmed/33656791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14778
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