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Tissue Inhibitor of Metalloproteinase-1 (TIMP-1) Promotes PMN Pericellular Proteolysis by Anchoring Matrix Metalloproteinase-8 and -9 to PMN Surfaces
Matrix metalloproteinase (MMP)-8 and -9 released by degranulating PMNs promote pericellular proteolysis by binding to PMN surfaces in catalytically-active, but tissue inhibitor of metalloproteinases (TIMP)-resistant forms. The PMN receptor(s) to which MMP-8 and MMP-9 bind(s) is not known. Competitiv...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7347292/ https://ncbi.nlm.nih.gov/pubmed/31019060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801466 |
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