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RhoGAP19D inhibits Cdc42 laterally to control epithelial cell shape and prevent invasion
Cdc42-GTP is required for apical domain formation in epithelial cells, where it recruits and activates the Par-6–aPKC polarity complex, but how the activity of Cdc42 itself is restricted apically is unclear. We used sequence analysis and 3D structural modeling to determine which Drosophila GTPase-ac...
Gorde:
| Argitaratua izan da: | J Cell Biol |
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| Egile Nagusiak: | , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Rockefeller University Press
2021
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7927664/ https://ncbi.nlm.nih.gov/pubmed/33646271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202009116 |
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