Synthesis, Neuroprotection, and Antioxidant Activity of 1,1′-Biphenylnitrones as α-Phenyl-N-tert-butylnitrone Analogues in In Vitro Ischemia Models

Herein, we report the neuroprotective and antioxidant activity of 1,1′-biphenyl nitrones (BPNs) 1–5 as α-phenyl-N-tert-butylnitrone analogues prepared from commercially available [1,1′-biphenyl]-4-carbaldehyde and [1,1′-biphenyl]-4,4′-dicarbaldehyde. The neuroprotection of BPNs 1-5 has been measured...

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Publicado no:Molecules
Main Authors: Chamorro, Beatriz, García-Vieira, David, Diez-Iriepa, Daniel, Garagarza, Estíbaliz, Chioua, Mourad, Hadjipavlou-Litina, Dimitra, López-Muñoz, Francisco, Marco-Contelles, José, Oset-Gasque, María Jesús
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7926640/
https://ncbi.nlm.nih.gov/pubmed/33672652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26041127
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