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Towards a comprehensive view of 8-oxo-7,8-dihydro-2’-deoxyguanosine: Highlighting the intertwined roles of DNA damage and epigenetics in genomic instability
8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG), a major product of DNA oxidation, is a pre-mutagenic lesion which is prone to mispair, if left unrepaired, with 2′-deoxyadenosine during DNA replication. While unrepaired or incompletely repaired 8-oxodG has classically been associated with genome insta...
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| Udgivet i: | DNA Repair (Amst) |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7926032/ https://ncbi.nlm.nih.gov/pubmed/33285475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2020.103027 |
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