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Multi-omics analysis reveals contextual tumor suppressive and oncogenic gene modules within the acute hypoxic response
Cellular adaptation to hypoxia is a hallmark of cancer, but the relative contribution of hypoxia-inducible factors (HIFs) versus other oxygen sensors to tumorigenesis is unclear. We employ a multi-omics pipeline including measurements of nascent RNA to characterize transcriptional changes upon acute...
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| Vydáno v: | Nat Commun |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7925689/ https://ncbi.nlm.nih.gov/pubmed/33654095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21687-2 |
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