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Altered metabolic and inflammatory transcriptomics after cardiac surgery in neonates with congenital heart disease

The study examines the whole blood transcriptome profile before and after cardiopulmonary bypass (CPB) in neonates with hypoplastic left heart syndrome (HLHS), a severe form of congenital heart disease, that can develop low cardiac output syndrome (LCOS). Whole blood mRNA transcriptome profiles of 1...

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Vydáno v:Sci Rep
Hlavní autoři: Jain, Parag N., Robertson, Matthew, Lasa, Javier J., Shekerdemian, Lara, Guffey, Danielle, Zhang, Yuhao, Lingappan, Krithika, Checchia, Paul, Coarfa, Cristian
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925649/
https://ncbi.nlm.nih.gov/pubmed/33654130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83882-x
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