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Immune Deregulation in Sepsis and Septic Shock: Reversing Immune Paralysis by Targeting PD-1/PD-L1 Pathway

Sepsis remains a major problem for human health worldwide, thereby manifesting high rates of morbidity and mortality. Sepsis, once understood as a monophasic sustained hyperinflammation, is currently recognized as a dysregulated host response to infection, with both hyperinflammation and immunoparal...

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Bibliografiska uppgifter
I publikationen:Front Immunol
Huvudupphovsmän: Nakamori, Yuki, Park, Eun Jeong, Shimaoka, Motomu
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925640/
https://ncbi.nlm.nih.gov/pubmed/33679715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.624279
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