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A single-chain antibody generation system yielding CAR-T cells with superior antitumor function
Cancer immunotherapy using T cells redirected with chimeric antigen receptor (CAR) has shown a lot of promise. We have established a single-chain antibody (scFv) generation system in which scFv library-expressing CAR-T cells can be screened appropriately based on their antitumor functions. A variabl...
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| 出版年: | Commun Biol |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7925539/ https://ncbi.nlm.nih.gov/pubmed/33654176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01791-1 |
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