Identification of candidate genes and pathways in retinopathy of prematurity by whole exome sequencing of preterm infants enriched in phenotypic extremes

Retinopathy of prematurity (ROP) is a vasoproliferative retinal disease affecting premature infants. In addition to prematurity itself and oxygen treatment, genetic factors have been suggested to predispose to ROP. We aimed to identify potentially pathogenic genes and biological pathways associated...

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Published in:Sci Rep
Main Authors: Kim, Sang Jin, Sonmez, Kemal, Swan, Ryan, Campbell, J. Peter, Ostmo, Susan, Chan, R. V. Paul, Nagiel, Aaron, Drenser, Kimberly A., Berrocal, Audina M., Horowitz, Jason D., Li, Xiaohui, Chen, Yii-Der Ida, Taylor, Kent D., Simmons, Charles, Rotter, Jerome I., Chiang, Michael F.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925531/
https://ncbi.nlm.nih.gov/pubmed/33654115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83552-y
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