Notch-regulated Dendritic Cells Restrain Inflammation-associated Colorectal Carcinogenesis

Conventional dendritic cells (cDCs) play a central role in T-cell anti-tumor responses. We studied the significance of Notch-regulated DC immune responses in a mouse model of colitis-associated colorectal cancer (CRC) in which there is epithelial down-regulation of Notch/Hes1 signaling. This defect...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Wang, Lei, Yu, Shuiliang, Chan, Ernest R., Chen, Kai-Yuan, Liu, Cui, Che, Danian, Awadallah, Amad, Myers, Jay, Askew, David, Huang, Alex Y., Maillard, Ivan, Huang, Dan, Xin, Wei, Zhou, Lan
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925430/
https://ncbi.nlm.nih.gov/pubmed/33441309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-20-0428
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