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Subcellular localization of EZH2 phosphorylated at T367 stratifies metaplastic breast carcinoma subtypes

BACKGROUND: Metaplastic carcinoma is an aggressive, triple-negative breast cancer (TNBC) with differentiation towards squamous, spindle, or mesenchymal cell types. The molecular underpinnings of the histological subtypes are unclear. Our lab discovered a cytoplasmic function of EZH2, a transcription...

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Publicat a:Breast Cancer
Autors principals: McMullen, Emily R., Skala, Stephanie L., Gonzalez, Maria E., Djomehri, Sabra, Chandrashekar, Darshan Shimoga, Varambally, Sooryanarayana, Kleer, Celina G.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925348/
https://ncbi.nlm.nih.gov/pubmed/33247371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12282-020-01189-7
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