A Novel Live Attenuated Respiratory Syncytial Virus Vaccine Candidate with Mutations in the L Protein SAM Binding Site and the G Protein Cleavage Site Is Protective in Cotton Rats and a Rhesus Macaque

Respiratory syncytial virus (RSV) is the leading cause of acute lower respiratory tract infections in children of <5 years of age worldwide, infecting the majority of infants in their first year of life. Despite the widespread impact of this virus, no vaccine is currently available. For more than...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Jenkins, Tiffany, Wang, Rongzhang, Harder, Olivia, Xue, Miaoge, Chen, Phylip, Corry, Jacqueline, Walker, Christopher, Teng, Michael, Mejias, Asuncion, Ramilo, Octavio, Niewiesk, Stefan, Li, Jianrong, Peeples, Mark E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2021
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925107/
https://ncbi.nlm.nih.gov/pubmed/33177201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01568-20
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares