Identification of an Antiretroviral Small Molecule That Appears To Be a Host-Targeting Inhibitor of HIV-1 Assembly

Given the projected increase in multidrug-resistant HIV-1, there is an urgent need for development of antiretrovirals that act on virus life cycle stages not targeted by drugs currently in use. Host-targeting compounds are of particular interest because they can offer a high barrier to resistance. H...

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Bibliographic Details
Published in:J Virol
Main Authors: Reed, Jonathan C., Solas, Dennis, Kitaygorodskyy, Anatoliy, Freeman, Beverly, Ressler, Dylan T. B., Phuong, Daryl J., Swain, J. Victor, Matlack, Kent, Hurt, Clarence R., Lingappa, Vishwanath R., Lingappa, Jaisri R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2021
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925099/
https://ncbi.nlm.nih.gov/pubmed/33148797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00883-20
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