Identifying the assembly intermediate in which Gag first associates with unspliced HIV-1 RNA suggests a novel model for HIV-1 RNA packaging

During immature capsid assembly, HIV-1 genome packaging is initiated when Gag first associates with unspliced HIV-1 RNA by a poorly understood process. Previously, we defined a pathway of sequential intracellular HIV-1 capsid assembly intermediates; here we sought to identify the intermediate in whi...

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Publicado en:PLoS Pathog
Autores principales: Barajas, Brook C., Tanaka, Motoko, Robinson, Bridget A., Phuong, Daryl J., Chutiraka, Kasana, Reed, Jonathan C., Lingappa, Jaisri R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940231/
https://ncbi.nlm.nih.gov/pubmed/29664940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006977
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