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Using computational modelling to reveal mechanisms of epigenetic Polycomb control

The Polycomb system is essential for stable gene silencing in many organisms. This regulation is achieved in part through addition of the histone modifications H3K27me2/me3 by Polycomb Repressive Complex 2 (PRC2). These modifications are believed to be the causative epigenetic memory elements of PRC...

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Detalhes bibliográficos
Publicado no:Biochem Soc Trans
Main Authors: Lövkvist, Cecilia, Howard, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925002/
https://ncbi.nlm.nih.gov/pubmed/33616630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20190955
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