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A theoretical model of Polycomb/Trithorax action unites stable epigenetic memory and dynamic regulation

Polycomb and Trithorax group proteins maintain stable epigenetic memory of gene expression states for some genes, but many targets show highly dynamic regulation. Here we combine experiment and theory to examine the mechanistic basis of these different modes of regulation. We present a mathematical...

詳細記述

保存先:
書誌詳細
出版年:Nat Commun
主要な著者: Reinig, Jeannette, Ruge, Frank, Howard, Martin, Ringrose, Leonie
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7508846/
https://ncbi.nlm.nih.gov/pubmed/32963223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18507-4
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