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A theoretical model of Polycomb/Trithorax action unites stable epigenetic memory and dynamic regulation

Polycomb and Trithorax group proteins maintain stable epigenetic memory of gene expression states for some genes, but many targets show highly dynamic regulation. Here we combine experiment and theory to examine the mechanistic basis of these different modes of regulation. We present a mathematical...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Reinig, Jeannette, Ruge, Frank, Howard, Martin, Ringrose, Leonie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7508846/
https://ncbi.nlm.nih.gov/pubmed/32963223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18507-4
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