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A theoretical model of Polycomb/Trithorax action unites stable epigenetic memory and dynamic regulation
Polycomb and Trithorax group proteins maintain stable epigenetic memory of gene expression states for some genes, but many targets show highly dynamic regulation. Here we combine experiment and theory to examine the mechanistic basis of these different modes of regulation. We present a mathematical...
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| Publicat a: | Nat Commun |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7508846/ https://ncbi.nlm.nih.gov/pubmed/32963223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18507-4 |
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