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In Silico Simulation of the Systemic Drug Exposure Following the Topical Application of Opioid Analgesics in Patients with Cutaneous Lesions

The use of opioid analgesics in treating severe pain is frequently associated with putative adverse effects in humans. Topical agents that are shown to have high efficacy with a favorable safety profile in clinical settings are great alternatives for pain management of multimodal analgesia. However,...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Pharmaceutics
Päätekijät: Khotimchenko, Maksim, Antontsev, Victor, Chakravarty, Kaushik, Hou, Hypatia, Varshney, Jyotika
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924840/
https://ncbi.nlm.nih.gov/pubmed/33669957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13020284
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