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In Silico Simulation of the Systemic Drug Exposure Following the Topical Application of Opioid Analgesics in Patients with Cutaneous Lesions

The use of opioid analgesics in treating severe pain is frequently associated with putative adverse effects in humans. Topical agents that are shown to have high efficacy with a favorable safety profile in clinical settings are great alternatives for pain management of multimodal analgesia. However,...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Khotimchenko, Maksim, Antontsev, Victor, Chakravarty, Kaushik, Hou, Hypatia, Varshney, Jyotika
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924840/
https://ncbi.nlm.nih.gov/pubmed/33669957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13020284
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