TLR7 agonist, N6-LS and PGT121 delayed viral rebound in SHIV-infected macaques after antiretroviral therapy interruption

Toll-like receptor 7 (TLR7) agonist and PGT121 (broadly neutralizing antibody, bnAb) administration previously delayed viral rebound and induced SHIV remission. We evaluated the impact of GS-986 (TLR7 agonist) and dual bnAbs on viral rebound after antiretroviral therapy (ART) interruption. Rhesus ma...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:PLoS Pathog
Hauptverfasser: Hsu, Denise C., Schuetz, Alexandra, Imerbsin, Rawiwan, Silsorn, Decha, Pegu, Amarendra, Inthawong, Dutsadee, Sopanaporn, Jumpol, Visudhiphan, Pornsuk, Chuenarom, Weerawan, Keawboon, Boot, Shi, Wei, Robb, Merlin L., Mascola, John R., Geleziunas, Romas, Koup, Richard A., Barouch, Dan H., Michael, Nelson L., Vasan, Sandhya
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2021
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924766/
https://ncbi.nlm.nih.gov/pubmed/33600506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009339
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge