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Fructose Induces Fluconazole Resistance in Candida albicans through Activation of Mdr1 and Cdr1 Transporters

Candida albicans is a pathogenic fungus that is increasingly developing multidrug resistance (MDR), including resistance to azole drugs such as fluconazole (FLC). This is partially a result of the increased synthesis of membrane efflux transporters Cdr1p, Cdr2p, and Mdr1p. Although all these protein...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Suchodolski, Jakub, Krasowska, Anna
Format: Artigo
Language:Inglês
Published: MDPI 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924610/
https://ncbi.nlm.nih.gov/pubmed/33669913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22042127
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