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Novel Monoclonal Antibodies Targeting the RRM2 domain of Human TDP-43 Protein
Transactive response DNA-binding protein of 43 kilodaltons (TDP-43) is a 414 amino acid peptide that under physiologic conditions localizes to the nucleus and participates in the regulation of RNA metabolism through two RNA recognition motifs (RRM1 and RRM2). In neurodegenerative diseases, TDP-43 ma...
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| Veröffentlicht in: | Neurosci Lett |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7924408/ https://ncbi.nlm.nih.gov/pubmed/32905837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2020.135353 |
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