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SARS-CoV-2 B.1.1.7 and B.1.351 Spike variants bind human ACE2 with increased affinity

SARS-CoV2 being highly infectious has been particularly effective in causing widespread infection globally and more variants of SARS-CoV2 are constantly being reported with increased genomic surveillance. In particular, the focus is on mutations of Spike protein, which binds human ACE2 protein enabl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:bioRxiv
Hauptverfasser: Ramanathan, Muthukumar, Ferguson, Ian D., Miao, Weili, Khavari, Paul A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924271/
https://ncbi.nlm.nih.gov/pubmed/33655251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.02.22.432359
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