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SARS-CoV-2 B.1.1.7 and B.1.351 Spike variants bind human ACE2 with increased affinity

SARS-CoV2 being highly infectious has been particularly effective in causing widespread infection globally and more variants of SARS-CoV2 are constantly being reported with increased genomic surveillance. In particular, the focus is on mutations of Spike protein, which binds human ACE2 protein enabl...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Ramanathan, Muthukumar, Ferguson, Ian D., Miao, Weili, Khavari, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924271/
https://ncbi.nlm.nih.gov/pubmed/33655251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.02.22.432359
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