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Accurate SNV detection in single cells by transposon-based whole-genome amplification of complementary strands
Single-nucleotide variants (SNVs), pertinent to aging and disease, occur sporadically in the human genome, hence necessitating single-cell measurements. However, detection of single-cell SNVs suffers from false positives (FPs) due to intracellular single-stranded DNA damage and the process of whole-...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7923680/ https://ncbi.nlm.nih.gov/pubmed/33593904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2013106118 |
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