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A comparative study on the unified model based multifactor dimensionality reduction methods for identifying gene-gene interactions associated with the survival phenotype

BACKGROUND: For gene-gene interaction analysis, the multifactor dimensionality reduction (MDR) method has been widely employed to reduce multi-levels of gene-gene interactions into high- or low-risk groups using a binary attribute. For the survival phenotype, the Cox-MDR method has been proposed usi...

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Detalles Bibliográficos
Publicado en:BioData Min
Main Authors: Lee, Jung Wun, Lee, Seungyeoun
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7923479/
https://ncbi.nlm.nih.gov/pubmed/33648540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13040-021-00248-9
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