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Multivariate Cluster-Based Multifactor Dimensionality Reduction to Identify Genetic Interactions for Multiple Quantitative Phenotypes

To understand the pathophysiology of complex diseases, including hypertension, diabetes, and autism, deleterious phenotypes are unlikely due to the effects of single genes, but rather, gene-gene interactions (GGIs), which are widely analyzed by multifactor dimensionality reduction (MDR). Early MDR m...

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Publicado en:Biomed Res Int
Autores principales: Kim, Hyein, Jeong, Hoe-Bin, Jung, Hye-Young, Park, Taesung, Park, Mira
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657635/
https://ncbi.nlm.nih.gov/pubmed/31380425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4578983
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