Gene Correction Recovers Phagocytosis in Retinal Pigment Epithelium Derived from Retinitis Pigmentosa-Human-Induced Pluripotent Stem Cells

Hereditary retinal dystrophies (HRD) represent a significant cause of blindness, affecting mostly retinal pigment epithelium (RPE) and photoreceptors (PRs), and currently suffer from a lack of effective treatments. Highly specialized RPE and PR cells interact mutually in the functional retina, there...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Artero-Castro, Ana, Long, Kathleen, Bassett, Andrew, Ávila-Fernandez, Almudena, Cortón, Marta, Vidal-Puig, Antonio, Jendelova, Pavla, Rodriguez-Jimenez, Francisco Javier, Clemente, Eleonora, Ayuso, Carmen, Erceg, Slaven
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7923278/
https://ncbi.nlm.nih.gov/pubmed/33672445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22042092
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