Cardioprotective Effects of a Nonsteroidal Mineralocorticoid Receptor Blocker, Esaxerenone, in Dahl Salt-Sensitive Hypertensive Rats

We investigated the effects of esaxerenone, a novel, nonsteroidal, and selective mineralocorticoid receptor blocker, on cardiac function in Dahl salt-sensitive (DSS) rats. We provided 6-week-old DSS rats a high-salt diet (HSD, 8% NaCl). Following six weeks of HSD feeding (establishment of cardiac hy...

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Publicat a:Int J Mol Sci
Autors principals: Rahman, Asadur, Sawano, Tatsuya, Sen, Anupoma, Hossain, Akram, Jahan, Nourin, Kobara, Hideki, Masaki, Tsutomu, Kosaka, Shinji, Kitada, Kento, Nakano, Daisuke, Imamura, Takeshi, Ohsaki, Hiroyuki, Nishiyama, Akira
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7922950/
https://ncbi.nlm.nih.gov/pubmed/33669786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22042069
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